Biochemistry. In eukaryotes, energy for biological processes in form of ATP is generated in the inner mitochondrial membrane. A series of electron carriers pass electrons from reduced coenzymes (NADH and FADH2 resulting of glycolysis and citrate cycle) to molecular oxygen coupled to proton transport generating ATP and water.
The mitochondrial respiratory chain consists of five complexes of integral membrane proteins: complex I (NADH dehydrogenase), complex II (succinate dehydrogenase), complex III (cytochrome c reductase), complex IV (cytochrome c oxidase) , complex V (ATP synthase), and the hydrogen and electron carriers ubiquinone and cytochrome c.
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