Study type: Medical/biological study (experimental study)

Responses of neurons to an amplitude modulated microwave stimulus med./bio.

Published in: Neurosci Lett 2002; 333 (3): 175-178

Aim of study (acc. to author)

To investigate the effects of a pulsed radio frequency signal similar to the signal produced by global system for mobile communication (GSM) telephones on neurons of the avian brain.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 10 min
Exposure 2: 900 MHz
Modulation type: CW
Exposure duration: continuous for 10 min

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 10 min
Modulation
Modulation type pulsed
Duty cycle 12.5 %
Repetition frequency 217 Hz
Pulse type rectangular
Exposure setup
Exposure source
Chamber A tuned resonant RF cavity of 3λ length was used (23.5 cm diameter, 100.5 cm long) made of perforated metal producing a standing wave and fitted with two tuned RF stubs each 16.5 cm (λ/2) from opposite ends and thus 2λ from each other: one for emitting the signal and one for monitoring the frequency and power of the signal being synchronized in phase and intensity to the emitted signal.
Setup The anesthetized bird was mounted in a non-conducting plastic holder and placed inside the cavity such that its head was at the center exactly 1λ from the emitting stub and the demodulating stub. Consequently, the signal the bird's head received was exactly the signal at both of those locations. The amplified RF signal was switched between a matched load and the cable to the waveguide chamber by a single-pole, double-throw RF switch controlled by a digital signal from the computer program.
Additional info To record from neurons in the brain of the bird, a glass micro-electrode of 1-2 µm tip diameter was inserted through a small hole (4 mm) in the skull, and a silver reference electrode was inserted beneath the skin along the back of the head. Arranging the electrodes along the long axis of the cavity prevented them from acting as a loop antenna and electrically stimulating the cells.
Parameters
Measurand Value Type Method Mass Remarks
power density 0.1 mW/cm² peak value measured - up to 0.5 mW/cm²
SAR 0.05 W/kg mean calculated - -

Exposure 2

Main characteristics
Frequency 900 MHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 10 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
power density 0.1 mW/cm² peak value measured - up to 0.5 mW/cm²

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure

Main outcome of study (acc. to author)

The stimulation resulted in changes in the amount of neural activity by more than half of the brain cells. Most (76%) of the responding cells increased their rates of firing. The other cells exhibited a decrease in their rates of spontaneous activity.

Study character:

Study funded by

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