To compare the effects of a brief maternal hyperthermia induced by microwave irradiation during pregnancy on mouse brain development with the thermal effects induced by a 42°C hot water immersion.
Pregnant mice were exposed to microwave on day 13 of gestation and the number of pycnotic cells in the ventricular zone of the telencephalon was examined 9 h after treatment.
external antenna
| Frequency | 2.45 GHz |
|---|---|
| Type | |
| Exposure duration | 15 or 20 min on day 13 of gestation |
| Modulation type | pulsed |
|---|---|
| Pulse width | 15 s |
| Additional info |
15s on off scedule |
| Exposure source |
|
|---|---|
| Distance between exposed object and exposure source | 0.275 m |
| Additional info | mice (head covered with aluminium foil fixed styrofoam) |
The highest maternal core temperature during irradiation did not exceed 42.5°C. The respective incidence of pycnotic cells in the group exposed to microwaves for 15 and 20 min were 1.83% and 3.06%. Microwave exposure for 20 min had an effect that was comparable to that of immersion in 42°C hot water for 15 min. In addition, some mice were examined on day 18 of gestation, and some of their offspring were examined at 6 weeks of age in an investigation of long-term effects. Brain weight for the animals exposed to microwaves for 20 min was significantly lower than for the control group. And the numerical density of the neurons in the cerebrum was higher. The authors concluded that microwave exposure at the dose tested mainly has a thermal effect.
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