Study type: Medical/biological study (experimental study)

Experimental study of the effects of radiofrequency electromagnetic fields on animals with soft tissue wounds med./bio.

By: Detlavs I, Dombrovska L, Turauska A, Shkirmante B, Slutskii L
Published in: Sci Total Environ 1996; 180 (1): 35-42
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Aim of study (acc. to author)

To investigate the effects of frequency modulated and non-modulated radiofrequency electromagnetic fields (RF EMF) on the dermal wound healing in rats.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 53.53 GHz
Modulation type: CW
Exposure duration: 30 min/day for 5 days
Exposure 2: 42.19 GHz
Modulation type: CW
Exposure duration: 30 min/day for 5 days
Exposure 3: 42.19 GHz
Modulation type: FM
Exposure duration: 30 min/day for 5 days

Exposure 1

Main characteristics
Frequency 53.53 GHz
Type
Exposure duration 30 min/day for 5 days
Modulation
Modulation type CW
Exposure setup
Exposure source
  • not specified
Setup Rats were placed in special plastic boxes where the wounded region was exposed.
Additional info Wistar rats with 15 mm diameter circular full-thickness dermal wound.
Parameters
Measurand Value Type Method Mass Remarks
power density 100 W/m² unspecified - unspecified -

Exposure 2

Main characteristics
Frequency 42.19 GHz
Type
Exposure duration 30 min/day for 5 days
Modulation
Modulation type CW
Exposure setup
Exposure source
  • not specified
Setup Rats were placed in special plastic boxes where the wounded region was exposed.
Additional info Wistar rats with 15 mm diameter circular full-thickness dermal wound.
Parameters
Measurand Value Type Method Mass Remarks
power density 100 W/m² unspecified - unspecified -

Exposure 3

Main characteristics
Frequency 42.19 GHz
Type
Exposure duration 30 min/day for 5 days
Modulation
Modulation type FM
Modulation frequency 200 MHz
Exposure setup
Exposure source
  • not specified
Setup Rats were placed in special plastic boxes where the wounded region was exposed.
Additional info Wistar rats with 15 mm diameter circular full-thickness dermal wound.
Parameters
Measurand Value Type Method Mass Remarks
power density 100 W/m² unspecified - unspecified -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
  • dermis
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Striking differences were observed between the effects of non-modulated and frequency modulated EMF exposure on granulation-fibrous tissue of wounded dermis. Exposure without frequency modulation decreased the amount of glycoproteins and macromolecules and so the inflammatory exudation was diminished. Whereas frequency modulated EMF exposure leads to significantly elevated levels of hexoses and sialic acid, also a pronounced accumulation of collagenous proteins was found.

Study character:

Study funded by

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