Study type: Medical/biological study (experimental study)

Effects of electromagnetic fields of low frequency and low intensity on rat metabolism med./bio.

Published in: Biomagn Res Technol 2008; 6: 3

Aim of study (acc. to author)

This study should investigate whether the exposure to low frequency athermal electromagnetic fields exerts influence on basic metabolic processes in rats.

Background/further details

Altogether 16 male rats, eight adult animals in the age of 8-12 weeks, and eight aging animals in the age of 68-72 weeks were used. After the first blood drawing three rats died. Blood samples were collected first after a 15 days adaption period, second after first half of irradiation (after fourteen days), third after second half of irradiation, fourth after one week period without irradiation, and fifth after a second irradiation of fourteen days. The body weight was measured at the same time points. Exposure results were compared to normal physiological parameter values for this rat strain.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 31.6 Hz
Exposure duration: continuous for 50 days
Exposure 2: 31.6 Hz
Exposure duration: continuous for 50 days

Exposure 1

Main characteristics
Frequency 31.6 Hz
Type
Exposure duration continuous for 50 days
Exposure setup
Exposure source
Setup diameter of the coil: 75 cm; rats placed in the middle of the coil
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 40 µT - measured - -

Exposure 2

Main characteristics
Frequency 31.6 Hz
Type
Exposure duration continuous for 50 days
Exposure setup
Exposure source
Setup stack of 5 Helmholtz coils
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 35.5 µT minimum measured - -
magnetic flux density 51.6 µT maximum measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • before exposure
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

After seven weeks of exposure rats showed an increase in body weight compared to historical data. The blood glucose increased more in aging than in adult animals at the end of exposure. The circulating levels of specific free fatty acids revealed clear difference between the initial values and the final ones. A frequent finding of histopathological examination was hepatic glycogenosis.
In conclusion, these data give evidence that the long term exposure electromagnetic fields with a well defined frequency may have relevant effects on parameters such as body weight, blood glucose and fatty acid metabolism.

Study character:

Study funded by

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