Evaluation of genotoxic effects in human fibroblasts after intermittent exposure to 50 Hz electromagnetic fields: a confirmatory study med./bio.

Aim of study (acc. to author)

Background/further details

Endpoint

• genotoxicity/mutation: DNA damage (DNA single-strand breaks)

Exposure

• • 50/60 Hz
  • magnetic field
• • power transmission line

Extended view Compact view

Methods Endpoint/measurement parameters/methodology

• genotoxicity/mutation: DNA damage (alkaline comet assay)
• cell viability/cell division/proliferation: cell cycle kinetics (micronucleus assay); cell proliferation (proliferation index); binucleate cell index

Main outcome of study (acc. to author)

Study funded by

• European Union (EU)/European Commission
• Ministero dell' Università e della Ricerca (MIUR (formerly MURST (Ministero dell' Università e della Ricerca Scientifica e Tecnologica); Ministry of University and Research), Italy
• VERUM Foundation (Stiftung für Verhalten und Umwelt), Germany

Replicated studies

• Ivancsits S et al. (2003): Intermittent extremely low frequency electromagnetic fields cause DNA damage in a dose-dependent way
• Ivancsits S et al. (2002): Induction of DNA strand breaks by intermittent exposure to extremely-low-frequency electromagnetic fields in human diploid fibroblasts

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