Induction of kinetochore-positive and kinetochore-negative micronuclei in CHO cells by ELF magnetic fields and/or X-rays med./bio.

Aim of study (acc. to author)

Background/further details

Endpoint

• genotoxicity/mutation: chromosomal alteration (micronuclei formation)

Exposure

• • 50/60 Hz
  • magnetic field
  • also other exposures without EMF
• • co-exposure

Extended view Compact view

Methods Endpoint/measurement parameters/methodology

• genotoxicity/mutation: micronuclei formation, number of micronuclei in binucleated cells, micronucleus positive/negative (cytokinesis-block micronucleus assay, fluorescence microscopy, immunofluorescence PI&FITC staining using anti-kinetochore antibodies)

Main outcome of study (acc. to author)

Study funded by

• Ministry of Education, Culture, Sports, Science and Technology, Japan
• Research for Future Program, Japan Society for the Promotion of Science (JSPS), Japan

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