To investigate the effects of pulsed electromagnetic fields on regenerative capabillity of the peripheral nervous system in rats.
Direct nerve fibre regeneration as well as biochemical changes should be investigated by microscopy and enzymatic assays, respectively.
| Exposure | Parameters |
|---|---|
|
Exposure 1:
15 Hz
Modulation type:
pulsed
Exposure duration:
repeated daily exposure, 6 h/day for 4 weeks
|
|
| Frequency | 15 Hz |
|---|---|
| Type | |
| Waveform | |
| Exposure duration | repeated daily exposure, 6 h/day for 4 weeks |
| Modulation type | pulsed |
|---|---|
| Additional info |
the duty cycle of the magnetic signal consisted of 20 sawtooth pulses with a peak to peak separation between each pulse of 200 µs; these pulses were delivered for 5 ms followed by a refractory period of 62 ms |
| Exposure source |
|
|---|---|
| Chamber | Animal cages |
| Setup | Coils were placed above and along the total length of the animal cages (animals were not restrained). |
| Additional info | Animals were divided into the A, AS, T, TS, P and PS groups (n=8 each). AS, TS and PS were exposed whereas A, T and P were used as control. |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| magnetic flux density | 900 µT | - | measured | - | to 1800 µT |
Pulsed electromagnetic field application leads to a statistically significant increase of the regeneration index as well as an increase in the acivities of the enzymes acetyl cholinesterase and NAD specific isocitrate dehydrogenase.
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