Power-frequency fields and cancer review

Endpoint

• genotoxicity/mutation: genotoxic activity (different assay descriptions; in vivo & in vitro assessment of genotoxicity, mutagenesis, cytogenetic injury (e.g. chromosome aberration, micronucleus formation, strand breaks)
• cell viability/cell division/proliferation: cell growth
• cancer: carcinogenic activity; mechanisms of carcinogenesis; carcinogenesis models; epigenetic activity (different assay descriptions; tumor promotion of different tumors, enhancement of genotoxicity & neoplastic cell transformation); tumor growth
• effects on the immune system: general immune functions
• endocrine changes: melatonin excretion
• epidemiology: cancer (residential exposure of children, adults; occupational exposure; e.g. leukaemia, breast cancer, lymphoma, CNS cancer)
• dosimetry/technology: biophysics of electric and magnetic fields (terminology, field characteristics, biophysical effects/mechanisms)
• statistical and methodological issues (laboratory/epidemiological studies; publication and reporting bias)

Exposure

• • 50/60 Hz
  • electric field
  • magnetic field
  • also other exposures without EMF
• • power transmission line

Study funded by

• not stated/no funding

Related articles

• Boorman GA et al. (2000): Leukemia and lymphoma incidence in rodents exposed to low-frequency magnetic fields