Study type: Medical/biological study (experimental study)

Inhibition of proliferation of human lymphoma cells U937 by a 50 Hz electromagnetic field med./bio.

Published in: Cell Mol Biol 2001; 47: OL115-OL117

Aim of study (acc. to editor)

To study the effects of a 50 Hz electromagnetic field on cell proliferation of the human leukemic monocyte cell line U937.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 50 Hz
Exposure duration: continuous exposure for up to 4 days

Exposure 1

Main characteristics
Frequency 50 Hz
Type
Exposure duration continuous exposure for up to 4 days
Exposure setup
Exposure source
Setup coils wrapped around the culture bottle (25 cm²)
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 4.5 mT maximum - - -
magnetic flux density 0.3 mT minimum - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • before exposure
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

The data showed no difference between exposed cells and control cells in the range of 0.3-2 mT. However, stronger fields (≥2.5 mT) inhibited cell division. Magnetic fields of ≥3.5 mT killed ≥80% of the cells at the beginning.

Study character:

Study funded by

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