voltage-clamp technique

Physiology. A type of patch-clamp technique that is an electrophysiologic technique for studying cells and cell membranes. The voltage-clamp technique is a method in which the voltage across the membrane is controlled and current flow is measured in comparison to the current-clamp technique in which the current is controlled and the voltage is measured. This technique is used to study for example how nerve cells respond to neurotransmitters that act by opening membrane ion channels.

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