Cell biology. Externalization of phosphatidylserine on the cell surface is a general marker of cells in the early stage of apoptosis. The phospholipid phosphatidylserine is found almost exclusively on inner leaflet of the lipid bilayer of the cell membrane in intact cells. If it is shifted to the outer leaflet it is free accessible and marks the cell for phagocytosis by macrophages. Externalization of phosphatidylserine can be made visible by staining with FITC marked Annexin V.
Search for publications that include this term
This website uses cookies to provide you the best browsing experience. By continuing to use this website you accept our use of cookies.
