Study type: Medical/biological study (experimental study)

Genotoxic effects of mitomycin-c and microwave radiation on bovine lymphocytes med./bio.

By: Scarfi MR, Lioi MB, d'Ambrosio G, Massa R, Zeni O, Di Pietto R, Di Berardino D
Published in: Electro Magnetobiol 1996; 15 (2): 99-107
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Aim of study (acc. to author)

To ascertain whether microwave radiation may produce genotoxic effects, assessed by cytokinesis-block micronucleus assay, in bovine peripheral blood lymphocytes.

Background/further details

Mitomycin C was used as positive control for the micronucleus induction.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 9 GHz
Exposure duration: 10 min

General information

blood samples were treated in four groups: i) control = no treatment ii) exposure to EMF iii) addition of Mitromycin = MMC iv) exposure to EMF + MMC

Exposure 1

Main characteristics
Frequency 9 GHz
Type
Exposure duration 10 min
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
SAR 70 mW/g - calculated - -

Reference articles

  • d'Ambrosio G et al. (1995): Genotoxic Effects of Amplitude-Modulated Microwaves on Human Lymphocytes Exposed in Vitro under Controlled Conditions

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Microwave radiation induces a statistically significant increase in micronucleus frequency both with and without mitomycin C. The optimal dose of mitomycin C to induce micronucleus frequency increase in this species is 0.044 µg/ml.

Study character:

Study funded by