Study type: Medical/biological study (experimental study)

The effects of microwave radiation and heat on specific mutants of Salmonella typhimurium LT2 med./bio.

Published in: Radiat Res 1980; 82 (3): 511-517

Aim of study (acc. to author)

To investigate the effects of a 2450 MHz microwave exposure to different histidine auxotrophic mutants of the bacterium Salmonella typhimurium LT2 according to the Ames test.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Exposure duration: 2, 4, 6, 8, 9, 10, 11, 12, 13, 14, 15, 17, 20 and 23 sec

Exposure 1

Main characteristics
Frequency 2.45 GHz
Exposure duration 2, 4, 6, 8, 9, 10, 11, 12, 13, 14, 15, 17, 20 and 23 sec
Exposure setup
Exposure source
Setup Top agar tubes were placed in the microwave oven at points where the power density was the same.
Parameters
Measurand Value Type Method Mass Remarks
power density 5.1 W/cm² - calculated - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

A significant rise in the mutation rates was found with microwave exposure. During exposure a constant rise in temperature was observed (up to 100°C after 23 sec of irradiation). To exclude that heat alone did cause the significant rise in mutation rate, comparable thermal testings were conducted in water baths. The mechanism of cellular damage due to microwave radiation is unknown. The authors conclude that microwave radiation of 2450 MHz is a potent mutagen and therefor a potential carcinogenic agent for animals.

Study character:

Study funded by

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