In order to distinguish clastogenic from aneugenic activity of mutagens, the micronucleus test was used. Cytochalasin cytokinesis-blocked human lymphocytes from populations that had been occupationally exposed to three well-known mutagenic agents were analysed: vinyl chloride, ionizing and microwave radiation.
| Exposure | Parameters |
|---|---|
|
Exposure 1:
1.25–1.35 GHz
Modulation type:
pulsed
|
|
| Exposure 2: | - |
| Exposure 3: | - |
| Frequency | 1.25–1.35 GHz |
|---|---|
| Type | |
| Waveform |
| Modulation type | pulsed |
|---|
| Exposure source |
|
|---|---|
| Additional info | People who were occupationally exposed to MW, X-rays or vinyl chloride monomer. |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| power density | 10 µW/cm² | unspecified | measured | - | 20 mW/cm²; at the working place of the subject. |
| Type | |
|---|---|
| Waveform | |
| Additional info | frequency: 100 PHz |
| Exposure source |
|
|---|
No parameters are specified for this exposure.
No parameters are specified for this exposure.
The comparison of frequencies of size distribution of micronuclei in the lymphocytes of subjects exposed to each of the three mutagens showed that X-rays and microwaves were preferentially clastogens while vinyl chloride monomer showed aneugenic activity as well. Microwaves possess some mutagenic characteristics typical of chemical mutagens.
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