To examine the interaction of microwave irradiation and ethanol as they affect the blood-brain barrier: 1) how varying concentrations of ethanol alter the microwave-induced changes of the barrier's permeability to Evans blue, and 2) how ethanol affect temperature changes in the brain of microwave-exposed animals.
| Exposure | Parameters |
|---|---|
|
Exposure 1:
3.15 GHz
Modulation type:
CW
Exposure duration:
continuous for 15 min
|
|
| Frequency | 3.15 GHz |
|---|---|
| Type | |
| Waveform | |
| Polarization | |
| Exposure duration | continuous for 15 min |
| Modulation type | CW |
|---|
| Exposure source |
|
|---|---|
| Setup | animal was placed in a stereotaxic apparaturswith the microwave applicator was placed in firm contact with the dorsal surface of the animal`s head |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| power density | 3 W/cm² | effective value | calculated | - | - |
Irradiation of rats by 3.15 GHz continuos wave microwaves can produce intense hyperthermia and alteration of the permeability of the blood-brain barrier. This hyperthermia and change in permeability is diminished if rats are given intravenous doses of ethanol prior to irradiation. The results indicate that ethanol inhibits microwave-induced permeation of the blood-brain barrier through reduced heating of the brain.
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