Study type: Medical/biological study (experimental study)

Cerebrovascular permeability to 86Rb in the rat after exposure to pulsed microwaves med./bio.

By: Goldman H, Lin JC, Murphy S, Lin MF
Published in: Bioelectromagnetics 1984; 5 (3): 323-330
Download citation in RIS format

Aim of study (acc. to author)

Investigation of the effect of high levels of localized microwave irradiation on permeability of blood-brain barrier in rats.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: pulsed
Exposure duration: continuous for 5, 10 or 20 min

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration continuous for 5, 10 or 20 min
Modulation
Modulation type pulsed
Pulse width 10 µs
Repetition frequency 500 Hz
Additional info

rectangular pulses
Exposure setup
Exposure source
  • dielectrically loaded coaxial applicator (Elmed-15, Addison, IL) , aperture 14 mm diameter.
Setup The applicator was in direct contact with the left side of head. Controls were performed in an identical manner for 20 mins but without EMF.
Parameters
Measurand Value Type Method Mass Remarks
power density 5 W/cm² mean measured - 240 W/kg peak SAR in the brain

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

Pulsed 2450 MHz microwaves caused increased permeability of the blood-brain barrier in various brain regions, accompanied by increased brain temperature, cardiac output, blood PaO2, PaCO2, and pH in rats.

Study character:

Study funded by