Study type: Medical/biological study (experimental study)

The functional state of thymus cells following microwave exposure of endocrine glands med./bio.

By: Bogolyubov VM, Zubkova SM, Frenkel ID, Sokolova ZA, Laprun IB
Published in: Radiat Res 1988; 115 (1): 44-53
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Aim of study (acc. to author)

Different parts (hypothalamus, thymus, thyroid, and adrenal gland) of chinchilla rabbits were exposed in vivo by microwaves. The effects on isolated thymocytes were investigated in vitro.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 460 MHz
Exposure duration: 6 min daily for 10 days
  • power density: 120 mW/cm²
  • SAR: 19.5 W/kg (for group i))
  • SAR: 6.2 W/kg (for group ii))
  • SAR: 20.8 W/kg (for group iii))
  • SAR: 9.3 W/kg (for group iv))

General information

for exposure animals were divided into four groups: i) exposure of the head's vertex ii) exposure of the area overlaying the adrenal glands iii) exposure of the area overlaying the thyroid iv) exposure of the thymus

Exposure 1

Main characteristics
Frequency 460 MHz
Type
Exposure duration 6 min daily for 10 days
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 120 mW/cm² - - - -
SAR 19.5 W/kg - calculated partial body for group i)
SAR 6.2 W/kg - calculated partial body for group ii)
SAR 20.8 W/kg - calculated partial body for group iii)
SAR 9.3 W/kg - calculated partial body for group iv)

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Rearrangements in cytoplasmic and nuclear membranes, chromatin structure as well as changes in lipid peroxidation were observed. The observed effects depended on localization and number of exposures.

Study character:

Study funded by