Study type: Medical/biological study (experimental study)

Dual effects of microwaves on single Ca(2+)-activated K+ channels in cultured kidney cells Vero med./bio.

Published in: FEBS Lett 1995; 359 (1): 85-88

Aim of study (acc. to author)

To investigate the effects of a 42.25 GHz microwave exposure on singel calcium-activated potassium ion channels in cultured kidney cells.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 42.25 GHz
Exposure duration: 20-30 min

Exposure 1

Main characteristics
Frequency 42.25 GHz
Type
Exposure duration 20-30 min
Exposure setup
Exposure source
Distance between exposed object and exposure source 0.5 m
Parameters
Measurand Value Type Method Mass Remarks
power 16 mW - - - -
power density 100 µW/cm² - - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

It was observed that microwave irradiation was capable to alter the apparent affinity of the channels for calcium, as well as the Hill coefficient. The data suggest that the exposure alters the cooperativity and binding characteristics of the potassium channel by internal calcium. The findings depend on the initial calcium sensitivity of the channels which could be influenced by the applied amount of calcium.

Study character:

Study funded by

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