Study type: Medical/biological study (experimental study)

Preliminary microwave irradiation of water solutions changes their channel-modifying activity med./bio.

Published in: FEBS Lett 1995; 366 (1): 49-52

Aim of study (acc. to author)

To investigate the effects of a preliminary microwave irradiation of water solutions on their ion channel modifiying capability.

Background/further details

The water solutions were pre-exposed for 20-30 min and afterwards added to the cultured kidney cells.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 42.25 GHz
Modulation type: CW
Exposure duration: continuous; 20-30 min

Exposure 1

Main characteristics
Frequency 42.25 GHz
Type
Waveform
Charakteristic
Polarization
Exposure duration continuous; 20-30 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Distance between exposed object and exposure source 0.06 m
Chamber petri dish 6cm diameter
Parameters
Measurand Value Type Method Mass Remarks
power density 20 W/m² maximum estimated - -
power 57 mW unspecified - - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The open-probability state of the potassium channels was influenced by the amount of calcium ions added to the solution (high calcium amount means a low open-probability state and vice versa). Depending on the open-probability state of potassium channels the application of a pre-irradiated solution increases or decreases the open-probability state of the channels. At low initial channel acitivity the solution increases the former and at high initial channel activity the solution inhibits the channel. The nature of these findings is unknown.

Study character:

Study funded by

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