To investigate the effects of a 20 kHz pulsed magnetic field on embryogenesis in mice.
Five experiments differing only in the start of exposure were conducted (i.e. magnetic field exposure began on day 1 of gestation (experiment 1 and 2), on day 2, on day 5, and on day 7 in experiments 3, 4, and 5, respectively). All exposures continued until day 19 post conception.
Exposure | Parameters |
---|---|
Exposure 1:
20 kHz
Modulation type:
pulsed
Exposure duration:
12, 14, 18, or 19 days
|
|
Field strength apparently was measured, but details are not mentioned. The experimental field appeared homogenous, with an overlapping 39-46 µT static magnetic field.
Frequency | 20 kHz |
---|---|
Type | |
Exposure duration | 12, 14, 18, or 19 days |
Modulation type | pulsed |
---|---|
Rise time | 45 µs |
Fall time | 5 µs |
Repetition frequency | 20 Hz |
Exposure source | |
---|---|
Chamber | racks |
Setup | mice placed in cages kept in racks |
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
magnetic flux density | 15 µT | peak value | measured | - | - |
A significantly higher placental resorption rate was observed in all groups when compared with controles, except in experiment 5. A increased malformation rate was not seen in any of the groups. Body mass and lenght were significantly reduced only in experiment 5. The number of dead fetuses was affected in experiment 1.
The Authors annotated that the effects of magnetic field exposure might be strain-related, because an increased number of resorptions has not been observed in other strains of mice.
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