Cognitive impairment and neurogenotoxic effects in rats exposed to low-intensity microwave radiation med./bio.

Aim of study (acc. to author)

Background/further details

Endpoint

• effects on the neurological system: cognitive function, Hsp70 protein expression and DNA damage in the rat brain

Exposure

• • 900–2,450 MHz
  • 2.45 GHz
  • microwaves
• • mobile communications

Extended view Compact view

Methods Endpoint/measurement parameters/methodology

• genotoxicity/mutation: DNA damage in brain: single-strand breaks and double strand breaks (alkaline comet assay)
• molecular biosynthesis: stress response: level of heat shock protein 70 (Hsp70) in hippocampus homogenates (ELISA)
• cognitive/behavioral endpoints: learning and memory (elevated plus maze on two consecutive days), spatial memory (Morris water maze)
• thermoregulation: rectal temperature (before and after exposure)

Main outcome of study (acc. to author)

Study funded by

• Indian Council of Medical Research (ICMR), India

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