The effects of an acute or chronic whole body exposure of rats to a 2100 MHz electromagnetic field on histology and oxidative stress in the parotid glands should be investigated.
30 rats were randomly divided into the four following groups: a) control for 10-day exposure (n=6), b) control for 40-day exposure (n=6), c) 10-day exposure (n=9) and d) 40-day exposure (n=9).
| Exposure | Parameters |
|---|---|
|
Exposure 1:
2,100 MHz
Exposure duration:
continuous for 6 h/d on 5 d/week for 10 days
|
|
|
Exposure 2:
2,100 MHz
Exposure duration:
continuous for 6 h/d on 5 d/week for 40 days
|
|
| Frequency | 2,100 MHz |
|---|---|
| Type | |
| Charakteristic | |
| Exposure duration | continuous for 6 h/d on 5 d/week for 10 days |
| Exposure source | |
|---|---|
| Distance between exposed object and exposure source | 12 cm |
| Chamber | animals were kept in plexiglass cages (40 Œ 25 Œ 20 cm) at a temperature of 20-22°C |
| Setup | digitally modulated 3G signals were produced by a vector signal generator connected to the antenna in a temperature-controlled, shielded room; 12 cm distance between the antenna and heads of rats |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| electric field strength | 16 V/m | - | measured | - | - |
| SAR | 0.4 W/kg | - | calculated | whole body | - |
| Frequency | 2,100 MHz |
|---|---|
| Type | |
| Charakteristic | |
| Exposure duration | continuous for 6 h/d on 5 d/week for 40 days |
| Exposure source |
|
|---|
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| electric field strength | 16 V/m | - | measured | - | - |
| SAR | 0.4 W/kg | - | calculated | whole body | - |
The histopathological examinations revealed a significant variation in cell size in samples from the 40-day exposure (group d) compared to its control (group b). Further non-significant histopathological changes were found between exposure and control, with more changes in the 40-day exposure than in the 10-day exposure (group c). No significant differences in the biochemical parameters regarding oxidative stress could be found between exposure and control groups.
The authors conclude that a chronic whole body exposure of rats to a 2100 MHz electromagnetic field can provoke histopathological changes in the parotid gland.
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