Study type: Medical/biological study (experimental study)

What is the impact of electromagnetic waves on epileptic seizures? med./bio.

Published in: Med Sci Monit Basic Res 2013; 19: 141-145

Aim of study (acc. to author)

To study the effects of exposure to electromagnetic fields with different frequencies in a mouse epilepsy model.

Background/further details

180 mice were investigated: 1.) control group, 2.) exposure to 900 MHz, 3.) exposure to 700 MHz, 4.) exposure to 500 MHz, 5.) exposure to 300 MHz and 6.) exposure to 100 MHz. The groups were divided into subgroups and exposed for 2, 12 (or 10? Remark EMF-Portal: contradictory data) or 20 hours (10 mice per subgroup). After exposure, mice were injected with 60 mg/kg pentylenetetrazole. The control group was treated after the same duration like the exposure groups. Afterwards, mice were monitored for 20 minutes.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Exposure duration: continious for 2, 12 (10?) or 20 hours
-
Exposure 2: 700 MHz
Exposure duration: continious for 2, 12 (10?) or 20 hours
-
Exposure 3: 500 MHz
Exposure duration: continious for 2, 12 (10?) or 20 hours
-
Exposure 4: 300 MHz
Exposure duration: continious for 2, 12 (10?) or 20 hours
-
Exposure 5: 100 MHz
Exposure duration: continious for 2, 12 (10?) or 20 hours
-

General information

Reference article: Balanis, CA: Antenna Theory, Analysis, and Design, 2nd ed., John Wiley & Sons, New York, 1997; 249-338

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration continious for 2, 12 (10?) or 20 hours
Exposure setup
Exposure source
Parameters

No parameters are specified for this exposure.

Exposure 2

Main characteristics
Frequency 700 MHz
Type
Exposure duration continious for 2, 12 (10?) or 20 hours
Exposure setup
Exposure source
Parameters

No parameters are specified for this exposure.

Exposure 3

Main characteristics
Frequency 500 MHz
Type
Exposure duration continious for 2, 12 (10?) or 20 hours
Exposure setup
Exposure source
Parameters

No parameters are specified for this exposure.

Exposure 4

Main characteristics
Frequency 300 MHz
Type
Exposure duration continious for 2, 12 (10?) or 20 hours
Exposure setup
Exposure source
Parameters

No parameters are specified for this exposure.

Exposure 5

Main characteristics
Frequency 100 MHz
Type
Exposure duration continious for 2, 12 (10?) or 20 hours
Exposure setup
Exposure source
Parameters

No parameters are specified for this exposure.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The mean latency to onset of initial seizure of the 2 hours-exposed group was significantly shorter than those of the 12 and 20 hours-exposed groups. There was a significant difference in the latency to onset of initial seizure between the mean (?) values of the control group and the 2 and 10 (12?) hours-exposed group (remark EMF-Portal: not clear what difference).
No statistically significant differences were found in the latencies of the most severe reaction.

Study character:

Study funded by

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