To study whether 50 Hz magnetic fields (1 mT and 6 mT) have any effects on platelet aggregation.
Blood from 80 healthy volunteers was anti-coagulated with either sodium citrate or heparin (n=40 each). Each sample was divided in an exposed and a sham exposed sample. Adenosine diphosphate, collagen, and epinephrine were used as aggregation inducing agents. 60 samples (30 sodium citrate, 30 heparin) were exposed at 1 mT, 20 samples were exposed at 6 mT (10 sodium citrate, 10 heparin).
Exposure | Parameters |
---|---|
Exposure 1:
50 Hz
Exposure duration:
continuous for 1.5 h
|
|
Exposure 2:
50 Hz
Exposure duration:
continuous for 1 h
|
|
Frequency | 50 Hz |
---|---|
Type | |
Exposure duration | continuous for 1.5 h |
Exposure source | |
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Setup | two coils were connected in series; coils were built using a 2 mm copper wire wound on a circular frame of 50 cm diameter (350 turns in each coil) |
Sham exposure | A sham exposure was conducted. |
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
magnetic flux density | 1 mT | - | measured | - | ± 0.05 mT (at the center of the coils) |
Frequency | 50 Hz |
---|---|
Type | |
Exposure duration | continuous for 1 h |
Exposure source |
|
---|---|
Sham exposure | A sham exposure was conducted. |
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
magnetic flux density | 6 mT | - | - | - | ± 0.05 mT (at the center of the coils) |
Exposure to a 1 mT 50 Hz magnetic field for 1.5 h had a significant effect on the aggregation parameters of collagen-induced aggregation in sodium citrate treated samples: the maximum values and slope of the collagen-induced aggregation curve were significantly increased. No significant differences were found in any other group.
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