The study is concerned with the appearance of bursting in the spontaneous activity of pacemaker neurons in response to pulsed waves and continuous wave radiation by microwaves.
| Frequency | 900 MHz |
|---|---|
| Type | |
| Charakteristic |
|
| Exposure duration | continuous for up to 15 min |
| Exposure source | |
|---|---|
| Chamber | The experimental techniques and systems were identical to those described in detail by Alekseev et al. [1986]. |
| Setup | The holding chamber was inserted into the center of a waveguide through an access port that was covered by a metallic mesh (1 x 1 mm) during the experiment. |
| Additional info | The temperature of the preparation was controlled by a flow of the medium through the chamber and did not rise by more than 0.1 °C up to an SAR of 20 W/kg. A desired increase of temperature was achieved by heating the medium by 3 °C and regulating the flow rate. |
It was found that pulsed waves but not continuous waves elicit bursting responses of neurons. Within the limits of experimental error the effect did not depend on the modulation frequency, but it was sensitive to the SAR. Mediator-induced, current activation of acetylcholine, serotonin, dopamine, or GABA receptors of the neuronal soma was not altered during exposures (continuous wave or pulsed waves) and could not have been responsible for the bursting effect.
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