To study whether radiofrequency exposure at 835 MHz (CDMA) affected changes in the expression of calcium binding proteins like calbindin-D(28k) and calretinin in the mouse hippocampus at SAR values of 1.6 W/kg and 4 W/kg at different exposure durations.
Radiofrequency exposure might alter intracellular signaling pathways through changes in calcium permeability across cell membranes. Changes in the expression of calcium binding proteins could indicate impaired Ca2+ homeostasis.
60 mice were divided into six groups (each n=10): 1) control group, 2) 1.6 W/kg exposure group (1 h, 5 days), 3) 4 W/kg exposure group (1 h, 5 days), 4) 1.6 W/kg exposure group (5 h, 1 day), 5) 4 W/kg exposure group (5 h, 1 day), 6) one month exposure group. Animals were sacrificed three hours following the terminal exposure.
| Frequency | 835 MHz |
|---|---|
| Type | |
| Exposure duration | continuous exposure for up to one month (see details) |
| Modulation type | cf. additional info |
|---|---|
| Additional info |
The body weights of the different groups did not change significantly. The data showed an almost complete pyramidal cell loss in the hippocampal CA1 area of mice exposed to electromagnetic fields for one month (group 6). The authors conclude that 835 MHz radiofrequency exposure may be harmful.
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