To study the effects of microwave exposure on DNA damage in rats and to assess whether microwave-induced DNA damage is basal or whether it is also generated through reactive oxygen species formation.
Eight rats were exposed and eight rats were sham-exposed. A modified comet assay was used to increase the sensitivity and to detect oxidative DNA damage.
This article has been retracted at the request of the Editors-in-Chief (further details).
| Exposure | Parameters |
|---|---|
|
Exposure 1:
915 MHz
Modulation type:
pulsed
Exposure duration:
continuous for 1 h/day, 7 days/week for 2 weeks
|
|
| Frequency | 915 MHz |
|---|---|
| Type | |
| Exposure duration | continuous for 1 h/day, 7 days/week for 2 weeks |
| Modulation type | pulsed |
|---|---|
| Additional info |
| Exposure source | |
|---|---|
| Setup | animals placed in individual 25 cm x 7.5 cm x 7.5 cm Plexiglas cages inside the GTEM cell |
| Sham exposure | A sham exposure was conducted. |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| power density | 2.4 W/m² | - | - | - | - |
| electric field strength | 30 V/m | - | - | - | uniform over the animal's body |
| SAR | 0.6 W/kg | average over mass | - | whole body | - |
Both the standard and the Fpg-modified comet assay detected increased DNA damage in blood leukocytes of the exposed rats. The significant increase in the Fpg-detected DNA damage suggests that oxidative stress is likely to be responsible. DNA damage detected by the standard comet assay indicates that some other mechanisms may also be involved.
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