Study type:
Epidemiological study
(observational study)
Occupational exposure to magnetic fields and the risk of brain tumors
epidem.
By:
Coble JB, Dosemeci M, Stewart PA, Blair A, Bowman J, Fine HA, Shapiro WR, Selker RG, Loeffler JS, Black PM, Linet MS, Inskip PD
Published in: Neuro Oncol 2009; 11 (3): 242-249
Aim of study (acc. to author)
Endpoint/type of risk estimation
Type of risk estimation:
(odds ratio (OR))
Exposure
Assessment
- questionnaire: lifetime occupational history included job title, type of industry, years started and stopped, and type of employment (e.g., full-time, part-time, or seasonal) for all jobs held for at least 6 months during lifetime; more detailed questions on job titles with a potential exposure to magnetic fields (tasks performed at work, type and size of electrically powered tools or equipment used, average distance from this equipment, and the amount of time spent working with or near electrically powered equipment)
- job exposure matrix: adjustment of exposure estimates based on job-specific questionnaires
Exposure groups
Group
|
Description
|
Reference group 1
|
maximum exposed job: ≤ 0.15 µT
|
Group 2
|
maximum exposed job: > 1.5 - 0.3 µT
|
Group 3
|
maximum exposed job: ≥ 0.3 µT
|
Reference group 4
|
duration > 0.15 µT: 0 year
|
Group 5
|
duration > 0.15 µT: > 0 - 15 years
|
Group 6
|
duration > 0.15 µT: > 15 years
|
Reference group 7
|
lifetime average: ≤ 0.15 µT
|
Group 8
|
lifetime average: > 0.15 - 0.3 µT
|
Group 9
|
lifetime average: ≥ 0.3 µT
|
Reference group 10
|
cumulative exposure > 0.15 µT: 0
|
Group 11
|
cumulative exposure > 0.15 µT: > 0 - 0.45 µT-years
|
Group 12
|
cumulative exposure > 0.15 µT: > 0.45 µT µT-years
|
Population
-
Group:
-
Observation period:
1994 - 1998
-
Study location:
USA (Phoenix, Arizona; Boston, Massachusetts, and Pittsburgh, Pennsylvania)
Case group
Control group
-
Selection:
- hospital-based
- cases for conditions other than cancer, including trauma, diseases of the circulatory and muscuoskeletal systems
-
Matching:
- sex
- age
- area
- ethnicity
- distance of residence from hospital
Study size
|
Cases |
Controls |
Eligible |
686 |
799 |
Statistical analysis method:
- unconditional logistic regression
(
adjustment:
)
Results (acc. to author)
Study funded by
-
National Cancer Institute (NCI; U.S. National Institutes of Health), Maryland, USA
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