Study type: Medical/biological study (experimental study)

Microscopic observation of living cells during their exposure to modulated electromagnetic fields med./bio.

Published in: Bioelectrochemistry 2008; 74 (1): 9-15

Aim of study (acc. to author)

To study mitosis progression and mitosis duration during and after the exposure to the modulated radiofrequency fields.

Background/further details

A TEM cell with holes was developed to allow the cell microscopic visualization during 1 h GSM electromagnetic field exposure of 2.2 W/kg (SAR value), at 30°C, in culture medium.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 900 MHz
Modulation type: pulsed
Exposure duration: continuous for 1 h
  • SAR: 2.2 W/kg

Exposure 1

Main characteristics
Frequency 900 MHz
Type
Exposure duration continuous for 1 h
Modulation
Modulation type pulsed
Pulse width 576 µs
Duty cycle 12.5 %
Repetition frequency 217 Hz
Pulse type rectangular
Exposure setup
Exposure source
Setup cells placed in aTEM cell inside an incubator
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 2.2 W/kg - calculated - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • before exposure
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

900 MHz GSM electromagnetic field exposure of 2.2 W/kg SAR value applied for 1 h did not affect either the mitosis progression or the mitosis duration in these experimental conditions. Endocytosis rate was increased (validating the use of the TEM cell).
The authors describe an improved experimental set-up which allows the continuous microscope cell observation during their exposure to GSM electromagnetic fields under well controlled conditions.

Study character:

Study funded by

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