To study whether chronic, high-level (1 mT) magnetic field exposure had an influence on lymphoma development in a mouse strain that is genetically predisposed to this disease.
The AKR/J mice genome carries a virus, which leads within one year to spontaneous development of thymic lymphoblastic lymphoma.
| Exposure | Parameters |
|---|---|
|
Exposure 1:
50 Hz
Exposure duration:
continuous for 24 h/day, 7 days a week for 32 weeks or until exitus
|
|
|
Exposure 2:
50 Hz
Exposure duration:
only during the night for 12 h/day, 7 days a week for 32 weeks or until exitus
|
|
| Frequency | 50 Hz |
|---|---|
| Type | |
| Waveform | |
| Exposure duration | continuous for 24 h/day, 7 days a week for 32 weeks or until exitus |
| Exposure source | |
|---|---|
| Setup | Ten randomly chosen cages (8 animals/cage; 40 x 25 x 30 cm³ lxwxh) were placed in one coil system of two outer and two inner rectangular coils. Two coil systems with anti-parallel wiring were used for sham exposure where as other two were designed to produce magnetic fields only during the dark phases. All coil systems were located in the same room (220 m²). |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| magnetic flux density | 1 mT | unspecified | measured | - | - |
| Frequency | 50 Hz |
|---|---|
| Type | |
| Waveform | |
| Exposure duration | only during the night for 12 h/day, 7 days a week for 32 weeks or until exitus |
| Exposure source |
|
|---|
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| magnetic flux density | 1 mT | unspecified | measured | - | - |
Exposure did not affect survival time, body weight, lymphoma development or hematological parameters. The results do not support the hypothesis that exposure to sinusoidal 50 Hz magnetic fields is a significant risk factor for hematopoietic diseases, even at this relatively high exposure level.
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