To study the effects of microwave irradiation from cellular phones on allergen-specific IgE production.
30 AEDS patients (atopic eczema/dermatitis syndrome) were studied. The patients were treated with application of mixture of pinetar and zinc oxide ointment, but without oral medication. All patients were positive for latex, but not to Japanese cedar pollen.
Normal subjects were also investigated.
Exposure | Parameters |
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Exposure 1:
800 MHz
Exposure duration:
continuous for 30 min
|
|
Details on frequency range and modulation were not provided in the article. They were obtained from the mobile phone specifications (Toshiba C5001T).
Frequency | 800 MHz |
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Type | |
Charakteristic |
|
Exposure duration | continuous for 30 min |
Exposure source | |
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Setup | The mobile phone "with transmitting but without sound" was placed to the right ear of the subjects while they watched a weather information video. |
Sham exposure | A sham exposure was conducted. |
Additional info | Two weeks after or before the exposure session, a double-blind control session was carried out with the phone switched off. |
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
SAR | 1.62 W/kg | unspecified | unspecified | unspecified | unit W/kg not indicated |
Non-exposure had no effect on allergen-specific IgE production, while exposure to microwave irradiation significantly increased allergen-specific IgE production. This increase was selective to allergen to which patients were allergic, as exposure increased latex-specific IgE production, while it failed to induce Japanese cedar pollen production.
The amount of allergen-specific IgE production was dependent on balance of Th1 cytokine and Th2 cytokine. Microwave exposure significantly decreased latex-induced IFN-gamma and IL-12 production, while it significantly increased latex-induced IL-4 and IL-13 production. In contrast, microwave exposure had no effect on production of these cytokines by Japanese cedar pollen.
Peripheral mononuclear cells from normal donors, who were exposed to microwave irradiation, failed to induce latex-specific IgE production by latex or Japanese cedar pollen-specific IgE production by Japanese cedar pollen.
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