Study type: Medical/biological study (experimental study)

Effects of microwaves and ELF magnetic field on the phagocytic activity of variously treated rat macrophages med./bio.

By: Dasdag S, Sert C, Akdag MZ, Oflazoglu HD
Published in: Electro Magnetobiol 2001; 20 (2): 177-184
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Aim of study (acc. to author)

To investigate the effects of 9450 MHz microwaves and extremely low frequency magnetic fields on the phagocytic activity of rat macrophages in control rats and those treated with vitamins C and E.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 9.45 GHz
Exposure duration: 1 h/day for 21 days
Exposure 2: 50 Hz
Exposure duration: 3 h/day for 3 weeks

General information

Rats were divided into four groups: group 1 served as control, group 2 was MW (microwave) exposed, group 3 and 4 were MW exposed and injected with vitamin E (150 mg/Kg/day) and vitamin C 150 mg/kg/day), respectively.

Exposure 1

Main characteristics
Frequency 9.45 GHz
Type
Exposure duration 1 h/day for 21 days
Exposure setup
Exposure source
Chamber methacrylate cages (20 cm x 10.5 cm x 10 cm) with ventilation holes
Setup anechoic chamber (70 cm x 47 cm x 47 cm);
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 1.8 mW/g mean measured whole body determined by calorimetic method.
power density 2.65 mW/cm² - - - -

Exposure 2

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration 3 h/day for 3 weeks
Exposure setup
Exposure source
Chamber Methacrylate cages (20 cm x 10.5 cm x 10 cm)
Setup 2 pairs of circular Helmholtz coils; cages placed between the coils.
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 750 µT unspecified measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results of the microwave-exposed group showed that the microwave increased the phagocytic activity of rats treated additionally with vitamin C. The increase in phagocytic activity of other microwave-exposed groups and magnetic field-exposed groups were found to be not significant. Comparison of microwave-exposed and microwave-plus-vitamin-C-treated groups showed that vitamin C seemed to play an important role to increase the phagocytic activity of rats. The microwave parameters under investigation were not found to be foremost. Rectal temperature of groups exposed to microwaves were found to be significantly higher.

Study character:

Study funded by

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