Study type: Medical/biological study (experimental study)

Effects of 2.45 GHz microwaves on meiotic chromosomes of male CBA/CAY mice med./bio.

By: Manikowska-Czerska E, Czerski P, Leach WM
Published in: J Hered 1985; 76 (1): 71-73
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Aim of study (acc. to author)

To obtain information on the relative incidence of chromosomal abnormalities in meiotic cells after exposure of male mice to micowave irradiation.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: 30 min/day, 6 days a week for 2 consecutive weeks
  • SAR: 0.05 mW/g average over mass (whole body)
  • SAR: 0.5 mW/g average over mass (whole body)
  • SAR: 5 mW/g average over mass (whole body)
Exposure 2: 2.45 GHz
Modulation type: CW
Exposure duration: 30 min/day, 6 days a week for 2 consecutive weeks.
  • SAR: 5 mW/g average over mass (whole body)
  • SAR: 10 mW/g average over mass (whole body)
  • SAR: 20 mW/g average over mass (whole body)

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration 30 min/day, 6 days a week for 2 consecutive weeks
Modulation
Modulation type CW
Exposure setup
Exposure source
Setup mice semi restained by placing them into cylindrical polyethylene holders with their tails taped to the holder; the holder was placed centrally in the waveguide; animals were exposed tail to head with respect to the direction of propagation of the radiation
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 0.05 mW/g average over mass measured whole body -
SAR 0.5 mW/g average over mass measured whole body -
SAR 5 mW/g average over mass measured whole body -

Exposure 2

Main characteristics
Frequency 2.45 GHz
Type
Exposure duration 30 min/day, 6 days a week for 2 consecutive weeks.
Modulation
Modulation type CW
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
SAR 5 mW/g average over mass measured whole body -
SAR 10 mW/g average over mass measured whole body -
SAR 20 mW/g average over mass measured whole body -

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The results indicate interference with normal spermatogenesis during the exposure period. Translocations were observed at diakinesis and metaphase I in exposed animals. The yield of translocations increased with exposure, and varied nonlinearly with dose rate. An increase in incidence of univalents was found after exposure at 10 and 20 mW/g.

Study character:

Study funded by