Medical/biological study (experimental study)

Multinucleated giant cell appearance after whole body microwave irradiation of rats med./bio.

By: Trosic I

Published in: Int J Hyg Environ Health 2001; 204 (2-3): 133-138

To gather information about the influence of selected electromagnetic radiation on the kinetics of alveolar macrophages and the formation of multinucleated giant cells after whole body microwave irradiation of rats.

Exposure	Parameters
Exposure 1: 2.45 GHz Exposure duration: 2 hrs per day, 5 days a week for 30 days (animals killed on experimental days 1, 8, 16, 30)	power density: 50 W/m² minimum (corresponding SAR ca. 20 mW/g) power density: 150 W/m² maximum (corresponding SAR ca. 20 mW/g)

Frequency	2.45 GHz
Type	electromagnetic field
Exposure duration	2 hrs per day, 5 days a week for 30 days (animals killed on experimental days 1, 8, 16, 30)

Exposure source	not specified
Chamber	Plexiglass cages

Measurand	Value	Type	Method	Mass	Remarks
power density	50 W/m²	minimum	unspecified	-	corresponding SAR ca. 20 mW/g
power density	150 W/m²	maximum	unspecified	-	corresponding SAR ca. 20 mW/g

Trosic I et al. (1999): Animal study on electromagnetic field biological potency

Exposed system:

Investigated system:

Investigated organ system:

Time of investigation:

Total cell number slightly decreased in treated animals showing time- and dose-dependance. Cell viability did not significantly change in the irradiated animal group. Binucleation and multinucleation of alveolar macrophages were sensitive time- and dose-dependent morphological indicators of pulmonary stress.

Study character:

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