Study type: Medical/biological study (experimental study)

Lack of effect of 94 GHz radio frequency radiation exposure in an animal model of skin carcinogenesis med./bio.

By: Mason PA, Walters TJ, DiGiovanni J, Beason CW, Jauchem JR, Dick Jr EJ, Mahajan K, Dusch SJ, Shields BA, Merritt JH, Murphy MR, Ryan KL
Published in: Carcinogenesis 2001; 22 (10): 1701-1708
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Aim of study (acc. to author)

To investigate whether a single or repeated exposure to 94 GHz radio frequency radiation serves as a promoter or copromoter in the 7,12-dimethylbenz[a]anthracene (DMBA)-induced SENCAR mouse model of skin carcinogenesis.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 94 GHz
Modulation type: CW
Exposure duration: 10 s
Exposure 2: 94 GHz
Modulation type: CW
Exposure duration: 2 exposures each for 10 s/week for 12 weeks

Exposure 1

Main characteristics
Frequency 94 GHz
Type
Charakteristic
Exposure duration 10 s
Modulation
Modulation type CW
Exposure setup
Exposure source
Chamber Plexiglass cages / 41 cm x 21 cm x 20 cm
Setup Each animal was exposed in a Styrofoam restrainer where a rectangular region (2.25 cm x 3 cm) was removed from the top of the restrainer.
Additional info A dielectric lens was placed 88 cm from the horn. A 45° aluminum reflector was placed 120 cm from the lens to aim the EMF towards the animal`s dorsal surface. The animal was located 60 cm below the aluminum reflector.
Parameters
Measurand Value Type Method Mass Remarks
power density 1 W/cm² unspecified - - -

Exposure 2

Main characteristics
Frequency 94 GHz
Type
Charakteristic
Exposure duration 2 exposures each for 10 s/week for 12 weeks
Modulation
Modulation type CW
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
power density 333 mW/cm² unspecified - - -
Additional parameter details

Animals were also exposed to IR of 1.5 W/cm² for 10 s.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

Exposure to 94 GHz radio frequency radiation under these conditions does not promote or copromote papilloma development in this animal model of skin carcinogenesis.

Study character:

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