To study the effects of prolonged exposure to low-intensity microwave fields on heat shock (HSP) responses in transgenic Caenorhabditis elegans.
Exposure | Parameters |
---|---|
Exposure 1:
750 MHz
Modulation type:
CW
Exposure duration:
continuous for 18 h
|
|
Frequency | 750 MHz |
---|---|
Type | |
Charakteristic |
|
Exposure duration | continuous for 18 h |
Modulation type | CW |
---|
Exposure source |
|
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Chamber | Incubator temperatures of 24.0, 24.5, 25.0 and 25.5 °C were tested using 12 replicates for each condition. Controls (6 replicates) were also run at 22, 26, 27 and 28 °C. |
Additional info | Temperature control worm cultures were shielded with aluminium foil and placed in the same incubator. Baseline controls were maintained at 15°C. |
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
power | 0.5 W | - | - | - | - |
electric field strength | 45 V/m | - | - | - | at the center of the TEM cell |
SAR | 0.001 W/kg | - | calculated | - | - |
It is shown that prolonged exposure to low-intensity microwave fields can induce heat shock protein responses. In exposed cultures, expression is comparable to that of controls at 24°C, but then it rises steeply.
It is suggested that the induction of heat shock proteins described here could involve non-thermal mechanisms. These could include microwave disruption of the weak bonds that maintain the active folded forms of proteins, enhanced production of reactive oxygen species (ROS), or interference with cell-signalling pathways that affect HSP induction.
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