Study type: Medical/biological study (experimental study)

Pretraining exposure to physiologically patterned electromagnetic stimulation attenuates fear-conditioned analgesia med./bio.

By: Stewart LS, Persinger MA
Published in: Int J Neurosci 2000; 100 (1-4): 91-98
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Aim of study (acc. to author)

To study the effect of weak electromagnetic stimulation on the emergence of fear-conditioned analgesia in the adult rat.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
Modulation type: pulsed
Exposure duration: 30 min (either before or after conditioning session)

Exposure 1

Main characteristics
Frequency
Type
Waveform
Exposure duration 30 min (either before or after conditioning session)
Modulation
Modulation type pulsed
Pulse width 1 ms
Exposure setup
Exposure source
Chamber 28 x 20 x 20 cm plexiglass chamber with floor consisting of steel bars
Setup cages placed in aluminum racks; each rack wrapped by 72 turns of American wire gauge
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 300 nT minimum measured - -
magnetic flux density 500 nT maximum - - -
Additional parameter details

training conditions: ultrasonic sound 20kHz (60dB) and footshock (1 s) of 0.2mA (over 5 succesive days)

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Results suggested a statistically significant attenuation of fear-conditioned analgesia in animals exposed to electromagnetic stimulation prior to conditioning, whereas post-conditioning irradiation potentiated the reduction in pain sensitivity compared to baseline measures.
The present data suggest that the emergence of fear-conditioned responses is sensitive to whole body exposure to a magnetic field pattern.

Study character:

Study funded by