Study type: Medical/biological study (experimental study)

Changes of hydration of rats' tissues after in vivo exposure to 0.2 Tesla steady magnetic field med./bio.

By: Danielyan AA, Ayrapetyan SN
Published in: Bioelectromagnetics 1999; 20 (2): 123-128
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Aim of study (acc. to author)

To investigate the effects of static magnetic field (SMF) on the hydration of different tissues of rat and the number of sodium potassium pump units.

Background/further details

Brain, liver, spleen, kidney, and heart tissue samples were investigated. The hydration state was determined by the following relation: (wet weight - dry weight)/dry weight.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
Exposure duration: 15 min, 30 min, 1 h, 2 h, 3.5-5 h

Exposure 1

Main characteristics
Frequency
Type
Exposure duration 15 min, 30 min, 1 h, 2 h, 3.5-5 h
Exposure setup
Exposure source
Setup Rats placed in special cages (7 cm x 14 cm) which corresponded to the width of the center of the gap of the magnet. Control rats were kept in the same cages for the same amount of time under the same conditions but in the absence of magnetic field.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 200 mT unspecified measured unspecified -
Measurement and calculation details

Magnetic field was measured with a Tesla meter.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

In brain and liver tissues in most of the rats a time-dependent decrease of hydration and adaption, followed by disadaption, could be detected after 3.5-5 h of exposure. The cell volume which correlates with the number of ouabain binding sites (as represented by sodium potassium pump units) was decreased in brain, liver, and spleen and increased in kidney tissue afer 30 min of exposure.

Study character:

Study funded by