To study the effect of extremely low frequency magnetic fields (50 Hz) on memory consolidation in adult male and female mice.
30 male and 30 female mice were divided into six groups (each group n=10): two exposure groups, two sham exposure groups and two control groups. Mice were exposed immediately after the "learning session" of the passive avoidance test. Tests were repeated 24 h after the learning session.
| Exposure | Parameters |
|---|---|
|
Exposure 1:
50 Hz
Exposure duration:
continuous for four hours
|
|
Male and female mice were divided into six groups; the follwing groups consisted of each one male and one female group: i) exposure group ii) sham exposure group iii) control group
| Frequency | 50 Hz |
|---|---|
| Type | |
| Waveform | |
| Exposure duration | continuous for four hours |
| Exposure source |
|
|---|---|
| Setup | characteristics of round coil: 1000 turns, copper wire (0,5 mm); dissipation of generated heat due to good ventilation in exposure area |
| Sham exposure | A sham exposure was conducted. |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| magnetic flux density | 8 mT | - | calibration | - | at the center of the coil |
The data showed that the exposure to an 8 mT, 50 Hz magnetic field for 4 h had adverse effects on memory consolidation in male and female mice (significant decreases in memory function: step-down latency lower).
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