The aim of this study was to examine the effects of extremely low frequency 1.5 mT magnetic field on the ocular conjunctiva in rats.
Goblet cells' function is to secrete mucus.
Thirty adult female rats (weighing 250-300 g) were assigned to exposure group and cage control, each containing 15 animals. Exposures were performed on animals which were not in estrous cycle.
| Exposure | Parameters |
|---|---|
|
Exposure 1:
50 Hz
Exposure duration:
continuous for 4 h/day for 7 days
|
|
| Frequency | 50 Hz |
|---|---|
| Type | |
| Exposure duration | continuous for 4 h/day for 7 days |
| Exposure source | |
|---|---|
| Setup | two pairs of Helmholtz coils with a diameter of 70 cm each, separated by 47 cm; placed inside a Faraday cage |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| magnetic flux density | 1.5 mT | - | measured | - | - |
In exposed rats, the number of goblet cells was less than the control group. Additionally, a significant decrease in goblet cell density was observed, accompanied by conjunctival edema and inflammation. Concerning fibroblast proliferation, an increase, but not statistical significant, was found in exposed rats.
These results suggest that the exposure to 50 Hz, 1.5 mT extremely low frequency magnetic field leads to morphological alterations of the conjunctiva which may cause dry eye symptoms.
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