Study type: Medical/biological study (experimental study)

The increased passive efflux of sodium and rubidium from rabbit erythrocytes by microwave radiation med./bio.

By: Olcerst RB, Belman S, Eisenbud M, Mumford WW, Rabinowitz JR
Published in: Radiat Res 1980; 82 (2): 244-256
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Aim of study (acc. to author)

To investigate the effects of 2450 MHz microwave exposure on the passive efflux of sodium and rubidium ions from rabbit erythrocytes under controlled temperature conditions.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Exposure duration: continuous for 1 h
  • SAR: 100 W/kg minimum (unspecified) (190 and 390 W/kg)

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Charakteristic
  • guided field
Exposure duration continuous for 1 h
Additional info Reference article: J.R.Rabinowitz, R.B.Olcerst, and W.W.Mumford. The description of a system to irradiate cells in culture with microwaves. In Biological Effects and Measurements of Radiofrequency/Microwave, pp. 216-226. HEW 77-8026, Bureau of Radiological Health, Washington DC, 1977.
Modulation
Modulation type unspecified
Exposure setup
Exposure source
Chamber A sample holder section which was used as a waveguide consisted of two concentric right cylindrical compartments, the inner compartment contains 1.5 ml sample and is surrounded by a jacketed section through which dodecane is circulated as heat exchange material.
Parameters
Measurand Value Type Method Mass Remarks
SAR 100 W/kg minimum measured and calculated unspecified 190 and 390 W/kg
Measurement and calculation details

SAR was determined by calorimetric techniques. Thermistors were placed in the inflow and outflow of the coolant served as a calorimeter that measured the total absorbed power in the sample cell.

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The cation efflux rate with microwave exposure was mainly identical to the control rates, except at three specific temperatures, where the exposure increased the efflux. One of these temperatures was examined in more detail with different specific absorbtion rates (SAR). Here, the efflux rates found for both cations were statistically greater than one would predict from a strictly thermal response.

Study character:

Study funded by