In both species there was an inverse relationship between ambient temperature and thresholdSAR to invoke an increase in breathing rate (ventilatory frequency). However, the thresholdSARs for mice were 270 to 450% higher than for hamsters (depending on ambient temperature). On the basis of rate of absorbed energy normalized to body weight (W/kg), mice can tolerate much more heat from microwaveirradiation than hamsters. The differences in sensitivity to microwaveirradiation in the mouse and hamster are probably attributable to species-specific characteristics (especially differences in body mass and, consequently, passive heat loss).