Study type: Medical/biological study (experimental study)

Verapamil protective effect on natural and artificial magnetic field cardiovascular impact med./bio.

By: Gmitrov J, Ohkubo C
Published in: Bioelectromagnetics 2002; 23 (7): 531-541
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Aim of study (acc. to author)

To investigate the interrelated effect of artificial static magnetic fields (SMF), natural geomagnetic fields (GMF), and verapamil on blood pressure regulation in rabbits. Verapamil is a calcium channel blocking agent.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
Exposure duration: 120 min (SMF series), 140 min (SMF+V series)

Exposure 1

Main characteristics
Frequency
Type
Exposure duration 120 min (SMF series), 140 min (SMF+V series)
Additional info Static MF
Exposure setup
Exposure source
  • 2 Nd(2)-Fe(14) alloy magnets with opposite poles hold by manipulators at an angle of 110 degrees
Additional info Rabbits inserted into copper drum with their head and neck out of it and manipulators with magnets positioned under sinocarotid baroreceptors of the rabbit's neck.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 350 mT unspecified measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:

Main outcome of study (acc. to author)

Disturbance in the geomagnetic field (GMF) decreased baroreceptor sensitivity, whereas static magnetic field (SMF) showed the opposite effect. Verapamil blocked the SMF and GMF effect on baroreceptor sensitivity. These findings indicate calcium channels as possible targets of exposure.

Study character:

Study funded by