Study type: Medical/biological study (experimental study)

Lack of effects on heart rate and blood pressure in ketamine-anesthetized rats briefly exposed to ultra-wideband electromagnetic pulses med./bio.

By: Jauchem JR, Frei MR, Ryan KL, Merritt JH, Murphy MR
Published in: IEEE Trans Biomed Eng 1999; 46 (1): 117-120
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Aim of study (acc. to editor)

To investigate heart rate and blood pressure changes in anesthetized rats exposed to ultra-wideband pulses.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 0–500 MHz
Modulation type: pulsed
Exposure duration: continuous for 0.5 and 5 s
Exposure 2: 0–500 MHz
Modulation type: pulsed
Exposure duration: intermittent, 2 s on/off, for 2 min

Exposure 1

Main characteristics
Frequency 0–500 MHz
Type
Waveform
Charakteristic
  • guided field
Exposure duration continuous for 0.5 and 5 s
Additional info total frequency range 0 Hz - 30 GHz with the dominant portion of the frequency spectrum in the range of o Hz - 500 MHz and the peak power density at 100 MHz
Modulation
Modulation type pulsed
Pulse width 6 ns
Rise time 327 ps
Repetition frequency 2 kHz
Additional info

rise time 318-337 ps
Exposure setup
Exposure source
Chamber The parallel plate transmission line was 1.5 ft wide, 1 ft between plates, and 4 ft long with microwave absorbers at the end.
Setup The anaesthetised animal was positioned on a Styrofoam block in the center of the exposure area (testing volume of 1 x 1.5 x 2 ft) with the head towards the antenna.
Additional info The 5 s exposures resulted in 2 s at the parameters listed and 3 s at slower rise times and higher peak fields which could, however, not be measured precisely.
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 21 kV/m peak value measured - 19-21 kV/m
Measurement and calculation details

The E-field was monitored with a 3 GHz D-dot probe. The waveform was measured with a multi GHz-bandpass system verification apparatus.

Exposure 2

Main characteristics
Frequency 0–500 MHz
Type
Waveform
Charakteristic
  • guided field
Exposure duration intermittent, 2 s on/off, for 2 min
Modulation
Modulation type pulsed
Pulse width 6 ns
Rise time 327 ps
Repetition frequency 1 kHz
Additional info

rise time 318-337 ps
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
electric field strength 21 kV/m peak value measured - 19-21 kV/m

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure

Main outcome of study (acc. to author)

The results suggest that acute whole-body exposure to ultra-wideband pulses does not have a detrimental effect on the cardiovascular system.

Study character:

Study funded by

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