Study type: Medical/biological study (experimental study)

Cerebrovascular permeability to sucrose in the rat exposed to 2,450-MHz microwaves med./bio.

By: Preston E, Prefontaine G
Published in: J Appl Physiol Respir Environ Exerc Physiol 1980; 49 (2): 218-223
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Aim of study (acc. to author)

To determine if 2450 MHz continuous-wave (CW) microwave energy increases permeability of the blood-brain barrier to sucrose.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2.45 GHz
Modulation type: CW
Exposure duration: continuous for 30 min
Exposure 2: 2.45 GHz
Modulation type: CW
Exposure duration: continuous; 25 min
  • SAR: 300 µW/g unspecified (partial body) (in the head)
  • SAR: 1.6 mW/g unspecified (partial body) (in the head)
  • SAR: 80 µW/g unspecified (partial body) (in the head)

Exposure 1

Main characteristics
Frequency 2.45 GHz
Type
Waveform
Charakteristic
Polarization
Exposure duration continuous for 30 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Distance between exposed object and exposure source 5 m
Chamber tapered anechoic chamber 8 x 3 x 3 m
Setup Anesthetized rat were placed prone on a support of foamed polysterene and acrylic sheet in the chamber quiet zone with nose toward antenna
Additional info Wave propagation was parallel to the floor of the chamber.
Parameters
Measurand Value Type Method Mass Remarks
power density 100 W/m² unspecified measured - at the midpoint of the chamber
power density 10 W/m² unspecified measured - at 0.58 m lateral to the boresight
Additional parameter details

SAR 0,1W/kg per 1 mWcm²

Exposure 2

Main characteristics
Frequency 2.45 GHz
Type
Waveform
Charakteristic
  • guided field
Polarization
Exposure duration continuous; 25 min
Modulation
Modulation type CW
Exposure setup
Exposure source
Distance between exposed object and exposure source 5 m
Chamber waveguide 11 x 3.5 x 1.6 cm with dielectricum, TE10 mode
Setup Anesthetized rats laying prone on a block of microwave absorber with the head mounted in a stereotaxic frame. Aperture was situated 1-3 mm above the skull surface of the rat
Parameters
Measurand Value Type Method Mass Remarks
SAR 300 µW/g unspecified measured and calculated partial body in the head
SAR 1.6 mW/g unspecified measured and calculated partial body in the head
SAR 80 µW/g unspecified measured and calculated partial body in the head

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure
  • after exposure

Main outcome of study (acc. to author)

Mean permeability-area (PA) product for brain regions from all microwave-treatment groups were not significantly elevated above mean values from sham-exposed rats.

Study character:

Study funded by