Study type: Medical/biological study (experimental study)

Microwave-induced chronotropic effects in the isolated rat heart med./bio.

By: Olsen RG, Lords JL, Durney CH
Published in: Ann Biomed Eng 1977; 5 (4): 395-409
Download citation in RIS format

Aim of study (acc. to author)

To investigate the effects of microwave exposure on the heart rate of isolated and perfused rat hearts in combination with use of atropine or propranolol. Atropine acts blocking at the parasympathetic nervous system, whereas propranolol acts blocking at the sympathetic nervous system.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 960 MHz
Modulation type: CW
  • SAR: 1.3 mW/g
Exposure 2: 960 MHz
Modulation type: CW
  • SAR: 2.1 mW/g

Exposure 1

Main characteristics
Frequency 960 MHz
Modulation
Modulation type CW
Exposure setup
Exposure source
  • parallel plate capacitor
Setup Heart was mounted on the centerline between the parallel plates
Additional info A brass screen Faraday shield (38 cm x 45 cm x 51 cm) was placed over the heart, strain gauge and the parallel plate irradiator.
Parameters
Measurand Value Type Method Mass Remarks
SAR 1.3 mW/g - calculated - -

Exposure 2

Main characteristics
Frequency 960 MHz
Modulation
Modulation type CW
Exposure setup
Exposure source
  • parallel plate capacitor
Setup Heart was mounted on the centerline between the parallel plates
Additional info A brass screen Faraday shield (38 cm x 45 cm x 51 cm) was placed over the heart, strain gauge and the parallel plate irradiator.
Parameters
Measurand Value Type Method Mass Remarks
SAR 2.1 mW/g - calculated - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • during exposure

Main outcome of study (acc. to author)

Microwave exposure induced bradycardia in isolated and perfused rat hearts. Hearts treated with atropin showed strong tachycardia during irradiation, even more stronger than atropin alone. On the other hand, hearts treated with propranolol showed stronger bradycardia during exposure than seen with propranolol alone.

Study character:

Study funded by