Study type: Medical/biological study (experimental study)

Permeability of the blood-brain barrier of the rat is not significantly altered by NMR exposure med./bio.

By: Liburdy RP, de Manincor DJ, Roos MS, Brennan KM
Published in: Ann N Y Acad Sci 1992; 649: 345-349
Download citation in RIS format

Aim of study (acc. to author)

To investigate the effects of NMR exposure on the permeability of the blood-brain barrier in rats.

Endpoint

Exposure

Exposure Parameters
Exposure 1: 100 MHz
Modulation type: pulsed
Exposure duration: continuous for 30 or 120 min

Exposure 1

Main characteristics
Frequency 100 MHz
Type
Exposure duration continuous for 30 or 120 min
Modulation
Modulation type pulsed
Exposure setup
Exposure source
  • magnet 40 cm bore; 2.35-T Bruker imaging spectrometer
Chamber Lucite restaining tubes
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 1 mT peak value - - -
magnetic flux density 64 µT mean - - -
Additional parameter details

dB/dt = 1 T/s

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

The findings of this study support the conclusion that 2.35 T NMR exposure is not capable to alter the permeability of the blood-brain barrier in rat.

Study character:

Study funded by