Study type: Medical/biological study (experimental study)

Psychoactive-drug response is affected by acute low-level microwave irradiation med./bio.

By: Lai H, Horita A, Chou CK, Guy AW
Published in: Bioelectromagnetics 1983; 4 (3): 205-214
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Aim of study (acc. to author)

To study the interaction between acute low-level microwave irradiation and the actions of several psychoactive drugs (apomorphine hydrochloride, d-amphetamine sulphate, and morphine sulphate).

Endpoint

Exposure

Exposure Parameters
Exposure 1: 2,450 MHz
Modulation type: pulsed
Exposure duration: continuous for 45 min

Exposure 1

Main characteristics
Frequency 2,450 MHz
Type
Charakteristic
  • guided field
Polarization
  • circular
Exposure duration continuous for 45 min
Modulation
Modulation type pulsed
Pulse width 2 µs
Repetition frequency 500 Hz
Exposure setup
Exposure source
Sham exposure A sham exposure was conducted.
Parameters
Measurand Value Type Method Mass Remarks
power density 1 mW/cm² mean estimated - -
SAR 0.6 W/kg - measured - calorimetry
Additional parameter details

The range of power densities in a linearly polarised plane wave at this SAR would approximate to 3 to 6 mW/cm² [Durney et al., 1978].

Reference articles

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Apomorphine-induced hypothermia and stereotypy were enhanced by exposure. Amphetamine-induced hyperthermia was attenuated while stereotypic behavior was unaffected. Morphine-induced catalepsy and lethality were enhanced by exposure at certain dosages of the drug. Since the drugs have different modes of action on central neural mechanism and the effects of microwaves depend on the particular drug investigated, these data show the complex nature of the effect of microwave exposure on brain functions.

Study character:

Study funded by