Study type: Medical/biological study (experimental study)

Sex differences in conditioned taste aversion and in the effects of exposure to a specific pulsed magnetic field in deer mice Peromyscus maniculatus med./bio.

By: Choleris E, Thomas AW, Ossenkopp K, Kavaliers M, Valsecchi P, Prato FS
Published in: Physiol Behav 2000; 71 (3-4): 237-249
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Aim of study (acc. to author)

To investigate the effects of pulsed magnetic field exposure on conditioned taste aversion in male and female deer mice (Peromyscus maniculatus augustus).

Background/further details

In a first experiment general conditioned taste aversion (in the absence of magnetic fileds) was investigated.
In a second experiment the effects of pulsed magnetic field exposure were studied.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
  • unspecified
Exposure duration: 60 min

Exposure 1

Main characteristics
Frequency
  • unspecified
Type
Waveform
Exposure duration 60 min
Modulation
Modulation type unspecified
Exposure setup
Exposure source
Setup mice were placed in a Plexiglas box (33 x 33 x 33 cm) in the center of the coils
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 100 µT peak value measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Without MF-exposure male and femal mice developed the same intensity in taste aversion, however male mice showing a longer duration of flavor adversion than femals. As a consequence of MF-exposure neither male nor femal mice developed a taste aversion. But a sex difference in response to MF-exposure was observed: male mice exhibited a significantly enhanced novel taste preference. This effect was not observed in femal mice.

Study character:

Study funded by

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